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Reviews in Cardiovascular Medicine  2019, Vol. 20 Issue (1): 41-46     DOI: 10.31083/j.rcm.2019.01.3281
Original Research Previous articles | Next articles
Differentiation of patients with two-dimensional echocardiography false positive non-compaction of ventricular myocardium by contrast echocardiography
Mingjun Tian1, Minjuan Zheng1, *(), Hui Ma1, Yicui Niu1, Ying Zhang1, Pan Xu1
1Department of Ultrasound, Xijing Hospital, Air Force Medical University, Xi'an, Shananxi 710032, P. R China
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Abstract:

Although echocardiography can be used to detect patients with non-compaction of the ventricular myocardium, it is often difficult to diagnose. In this study, the endocardium may be clearly visualized by contrast echocardiography to improve the diagnostic accuracy of patients with noncompaction of the ventricular myocardium. Twenty-four patients (n = 24) suspected with non-compaction of the ventricular myocardium Underwent transthoracic echocardiography including an intracardiac contrast echocardiography. The clinical data, Left ventricular opacification, and contrast echocardiography results were analyzed retrospectively. Twenty-four patients (n = 24) suspected with noncompaction of the ventricular myocardium were classified with transthoracic echocardiography and contrast echocardiography results into two groups: false positive and true positive. There were no significant differences in age, predisposing segments, Left Ventricular End-Diastolic Diameter, Left Ventricular End-Diastolic Volume, Left Ventricular End-Systolic Diameter, Left Ventricular End-Systolic Volume and ejection fraction between the two groups (P > 0.05). The thickness ratio of noncompacted to compacted myocardium (N/C) in the true positive group was significantly higher than that in the false positive group (3.47 ± 1.31 vs. 4.96 ± 1.28; P < 0.05). The range of noncompact myocardium in non-compaction of the ventricular myocardium patients can be observed clearly by Left ventricular opacification. Contrast medium in trabecular space and crypt is plentiful and ultrasonic contrast is more objective in measuring the thickness of dense myocardium. Two-dimensional echocardiography plays a characteristic role in the diagnosis of non-compaction of the ventricular myocardium; however, some suspected patients were observed to be false positive. Left ventricular opacification can greatly improve the clarity and accuracy of the endocardial margin by enhancing left ventricular imaging, displaying the true dense and non-dense layers, and improve the accuracy of ultrasonic diagnosis of noncompaction of the ventricular myocardium. The purpose of this paper was to explore the applied value of contrast echocardiography for heart diagnosis.

Key words:  Non-compaction of ventricular myocardium      cardiac contrast echocardiography      microbubble      false positive      echocardiography     
Published:  30 March 2019     
Fund: 
  • XJGX15Y16/FMMU Innovative technology project
  • 2018XD028/FMMU Science and Technology Development Fund Project
*Corresponding Author(s):  Minjuan Zheng     E-mail:  zhengmj@fmmu.edu.cn

Cite this article: 

Mingjun Tian, Minjuan Zheng, Hui Ma, Yicui Niu, Ying Zhang, Pan Xu. Differentiation of patients with two-dimensional echocardiography false positive non-compaction of ventricular myocardium by contrast echocardiography. Reviews in Cardiovascular Medicine, 2019, 20(1): 41-46.

URL: 

https://rcm.imrpress.com/EN/10.31083/j.rcm.2019.01.3281     OR     https://rcm.imrpress.com/EN/Y2019/V20/I1/41

Table 1  Index comparison table
Age ESV (ml) EDV (ml) EF (%) EDD (mm) ESD (mm)
fase-positive groups 29.50 ± 8.735 76.33 ± 16.133 129.67 ± 19.99 39.67% ± 7.84 56.75 ± 4.77 45.75 ± 6.20
NVM-positive groups 43.08 ± 14.66 63.75 ± 35.04 124.92 ± 40.66 51.54% ± 10.80% 53.23 ± 9.58 42.42 ± 8.96
Figure 1.  False-positive groups (A) Transthoracic echocardiography (B) Acoustic imaging

Figure 2.  NVM-positive groups (A) Transthoracic echocardiography (B) Acoustic imaging

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