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Reviews in Cardiovascular Medicine  2021, Vol. 22 Issue (3): 911-918     DOI: 10.31083/j.rcm2203098
Special Issue: Contemporary Management of Special Subsets of Acute Coronary Syndromes Patients
Original Research Previous articles | Next articles
Clinical characteristics and outcomes in acute myocardial infarction patients aged ≥65 years in Western Romania
Florina Caruntu1, 2, †, Diana Aurora Bordejevic1, 2, †, Mirela Cleopatra Tomescu1, 2, *(), Ioana Mihaela Citu1, 2
1Cardiology Clinic, Timisoara Municipal Clinical Emergency Hospital, 300024 Timișoara, Romania
2Multidisciplinary Heart Research Center, Victor Babeș University of Medicine and Pharmacy, 300041 Timișoara, Romania
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Abstract:
Older age is known as a negative prognostic parameter in patients with acute myocardial infarction (AMI). In this study, we aimed to investigate age-related differences in treatment protocols, in-hospital and 1-year mortality. This retrospective observational single-center study enrolled consecutive AMI patients with an urgent percutaneous coronary intervention (PCI) as the main method of myocardial revascularization. The patients divided were divided by age into group I (≥65 years) and group II (<65 years). The primary endpoint was in-hospital mortality, the secondary endpoints were 1-year mortality and rehospitalization rates. Of the 522 admitted with AMI, 476 were enrolled in the study. The mean age was 67 ± 13 years; 62% were men. Group I patients had a significantly lower rate of performed PCI (65% vs. 79%, P < 0.001). 53 patients (12.3%) died during hospitalization, and this proportion was notably higher in the older population (20% vs. 6%, P < 0.0001). The cardiac causes of death were more frequent in group I patients (12% vs. 5.6%, P = 0.016). The multivariate logistic regression selected two variables as independent predictors for the risk of in-hospital death: age ≥65 years (P = 0.0170), and Killip class at admission (P < 0.0001). The 1-year mortality was 3.3%, slightly higher in group I patients (4.8% vs. 1.5%, P = 0.05). In conclusion, patients aged ≥65 years have three times higher in-hospital mortality, but similar 1-year mortality and readmission rates when compared with the younger patients. It is obvious that there is a large potential for improvement of the AMI care in this age group of patients.
Key words:  Acute myocardial infarction      PCI      Age ≥65 years      Prognosis     
Submitted:  21 February 2021      Revised:  10 May 2021      Accepted:  21 June 2021      Published:  24 September 2021     
*Corresponding Author(s):  Mirela Cleopatra Tomescu     E-mail:  tomescu.mirela@umft.ro
About author:  These authors contributed equally.

Cite this article: 

Florina Caruntu, Diana Aurora Bordejevic, Mirela Cleopatra Tomescu, Ioana Mihaela Citu. Clinical characteristics and outcomes in acute myocardial infarction patients aged ≥65 years in Western Romania. Reviews in Cardiovascular Medicine, 2021, 22(3): 911-918.

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https://rcm.imrpress.com/EN/10.31083/j.rcm2203098     OR     https://rcm.imrpress.com/EN/Y2021/V22/I3/911

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