Please wait a minute...
Reviews in Cardiovascular Medicine  2018, Vol. 19 Issue (2): 65-68     DOI: 10.31083/j.rcm.2018.02.893
Case Review Previous articles | Next articles
Stress Cardiomyopathy in a Patient with Hypertrophic Cardiomyopathy: Case Presentation and Review of the Literature
Juan M. Vinardell1, Christos G. Mihos2, Adam Nader3, Richard Ro3, Esteban Escolar3, Orlando Santana3, *()
1 Department of Internal Medicine, Mount Sinai Medical Center, Miami Beach, Florida 33140
2 Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston MA 02114
3 Columbia University Division of Cardiology at the Mount Sinai Heart Institute, Miami Beach, Florida 33140
Download:  PDF(2378KB)  ( 886 )
Export:  BibTeX | EndNote (RIS)      
Stress cardiomyopathy and hypertrophic cardiomyopathy are two distinct entities with different pathophysiologic causes. In the recent medical literature their concurrency has been described. During the acute phase of a stress cardiomyopathy making the diagnosis of a concomitant hypertrophic cardiomyopathy may be challenging, and has important implications in both the acute and longterm clinical management. Herein, we present a case of a stress cardiomyopathy occurring in a patient with hypertrophic cardiomyopathy, along with a review of the literature.
Key words:  Hypertrophic cardiomyopathy      Stress cardiomyopathy      Hemodynamic instability      Myocardial edema      Mitral regurgitation     
Published:  30 June 2018     
*Corresponding Author(s):  Orlando Santana:, E-mail:   

Cite this article: 

Juan M. Vinardell, Christos G. Mihos, Adam Nader, Richard Ro, Esteban Escolar, Orlando Santana. Stress Cardiomyopathy in a Patient with Hypertrophic Cardiomyopathy: Case Presentation and Review of the Literature. Reviews in Cardiovascular Medicine, 2018, 19(2): 65-68.

URL:     OR

[1] Akashi YJ, Goldstein DS, Barbaro G, et al. Takotsubo cardiomyopathy: a new form of acute, reversible heart failure. Circulation. 2008;118:2754-2762.
[2] Brabham WW, Lewis GF, Bonnema DD, et al. Takotsubo cardiomyopathy in a patient with previously undiagnosed hypertrophic cardiomyopathy with obstruction. Cardiovasc Revascularization Med. 2011;12:70.e1-70.e5.
[3] Daralammori Y, El Garhy M, Gayed MR, et al. Hypertrophic obstructive cardiomyopathy masked by tako-tsubo syndrome: a case report. Case Reports Cardiol. 2012;2012:486427.
[4] Egea-serrano P, Keituqwa I, Pelaez A, et al. Hypertrophic obstructive cardiomyopathy and takotsubo syndrome : could they coexist ? Arch Cardiovasc Imaging. 2015;3:e36507.
[5] El Mahmoud R, Mansencal N, Pilliére R, et al. Prevalence and characteristics of left ventricular outflow tract obstruction in Tako-Tsubo syndrome. Am Heart J. 2008;156:543-548.
[6] Gziut AI, Piechocka E, Pawlowski T, et al. Tako-tsubo cardiomyopathy in a patient with hypertrophic cardiomyopathy with obstruction. Kardiol Pol. 2012;70:298-301.
[7] Izgi C, Ray S, Nyktari E, et al. Myocardial edema in takotsubo syndrome mimicking apical hypertrophic cardiomyopathy: An insight into diagnosis by cardiovascular magnetic resonance. Heart Lung. 2015;44:481-485.
[8] Jaber WA, Scott RW, Murphy J. A Patient with hypertrophic obstructive cardiomyopathy presenting with left ventricular apical ballooning syndrome. J Invasive Cardiol. 2006;18:510-512.
[9] Madias JE. Myocardial apical hypertrophy and takotsubo cardiomyopathy. Tex Heart Inst J. 2014;41:568.
[10] Maron BJ. The electrocardiogram as a diagnostic tool for hypertrophic cardiomyopathy: revisited. Ann Noninvasive Electrocardiol. 2001;6:277-279.
[11] Maron BJ, Ommen SR, Semsarian C, et al. Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine. J Am Coll Cardiol. 2014;64:83-99.
[12] Miyoshi S, Hara Y, Ogimoto A, et al. Repeated changes of electrocardiogram caused by Takotsubo-type cardiomyopathy: a case with hypertrophic nonobstructive cardiomyopathy. Nihon Ronen Igakkai Zasshi. 2005;42:112-115.
[14] Modi S, Ramsdale D. Tako-tsubo, hypertrophic obstructive cardiomyopathy & muscle bridging - Separate disease entities or a single condition? Int J Cardiol. 2011;147:133-134.
[14] Nascimento FO, Santana O, Perez-Caminero M, et al. The characteristics of stress cardiomyopathy in an ethnically heterogeneous population. Clinics. 2011;66:1895-1899.
[15] Ochiumi Y, Ikeda S, Hamada M. Reappearance of the left ventricular pressure gradient in a patient with hypertrophic obstructive cardiomyopathy. Intern Med. 2015;54:805-806.
[16] Pastor A, Petrillo F, Navarro M, et al. How far do we want to go in the treatment of obstruction in hypertrophic cardiomyopathy? Int J Cardiol. 2015;195:95-97.
[17] Patrianakos AP, Nyktari E, Parthenakis FI, et al. Reversible left ventricular apical ballooning after heavy alcohol consumption in a patient with hypertrophic cardiomyopathy. Int J Cardiol. 2013;164:e29-e31.
[18] Pelliccia F, Parodi G, Greco C, et al. Comorbidities frequency in Takotsubo syndrome: an international collaborative systematic review including 1109 patients. Am J Med. 2015;128:654.e11- e19.
[19] Roy RR, Hakim FA, Hurst RT et al. Two cases of apical ballooning syndrome masking apical hypertrophic cardiomyopathy. Tex Hear Inst J. 2014;41:179-183.
[20] Semsarian C, Ingles J, Maron MS, et al. New perspectives on the prevalence of hypertrophic cardiomyopathy. J Am Coll Cardiol. 2015;65:1249-1254.
[21] Silbiger JJ. Abnormalities of the mitral apparatus in hypertrophic cardiomyopathy: echocardiographic, pathophysiologic, and surgical insights. J Am Soc Echocardiogr. 2016;29:622-639.
[22] Singh NK, Rehman A, Hansalia SJ. Transient apical ballooning in hypertrophic obstructive cardiomyopathy. Tex Hear Inst J. 2008;35:483-484.
[1] Sarika K. Desai, Jerold Shinbane, Jayanta R. Das, James Mirocha, Suhail Dohad. Takotsubo Cardiomyopathy: Clinical Characteristics and Outcomes[J]. Reviews in Cardiovascular Medicine, 2015, 16(4): 244-252.
No Suggested Reading articles found!