TakoTsubo Syndrome (TTS) is an acute cardiac syndrome with heart failure features that poses important differential diagnostic questions with acute coronary syndrome. Though its classical form is known for the typical pattern of left ventricular apical ballooning, diverse wall motion abnormalities causing atypical presentations of ballooning can be observed in both ventricles. TTS is frequently triggered by physical or emotional stress and predominantly affects postmenopausal women. Importantly, complete recovery of systolic function is expected, as imaging techniques demonstrate absence of irreversible myocardial damage. However, observational studies carried out over the last 20 years and shedding light about epidemiology and clinical features have underscored unexpected prognostic implications of the disease. Patients with TTS exhibit a substantial risk of adverse events and even mortality and should be considered a vulnerable population. Pathophysiology of TTS remains largely elusive and to deeply understand mechanisms of the disease is essential to pave the way to specific treatments aimed at improving prognosis and, especially, prevent recurrences.
The present Special Issue is aimed at presenting what is known, what is the most recent evidence and what remains to be understood in the field of TTS. Therefore, submission of original research papers and review articles dealing with the pathophysiology, diagnosis, treatment, and prognosis of TTS is eagerly welcome.
Assistant Professor Giuseppe Andò
Manuscript Submission Information
Manuscripts should be submitted online at https://rcm.imrpress.org by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on theInstructions for Authorspage. Reviews in Cardiovascular Medicine is an international peer-reviewed open access quarterly journal published by IMR Press.