Coronary atherosclerosis is one of the leading cause of death in developed countries and one of the most investigated fields in cardiovascular medicine accounting for a huge part of the cost of health systems all over the world. Understanding pathophysiology is heavily linked to the chance of preventing or treat the clinical manifestations of coronary artery disease. New hypotheses and insights from basic science and medicine are currently been investigated or are in the pipeline to be translated into clinical practice. Basic science investigations about the contribution of new markers of disease to development of clinical apparent atherosclerosis are being undertaken in the most advanced centers. Computational and virtual simulation medicine is taking part as one of the newest tools in understanding pathophysiology of the atherosclerotic process and predicting fate of available endovascular therapy. At the same time, new drugs new imaging tools and new interventional techniques and protocols are being developed in order to improve diagnosis, clinical outcomes and prognosis of coronary atherosclerosis. The new special issues of Reviews in Cardiovascular Medicine (ISSN 1530-6550) is aimed to explore this exciting process of translation from basic science to clinical practice in the knowledge, diagnosis and treatment of coronary atherosclerosis.
Dr. Gianluca Rigatelli and Dr. Marco Zuin
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