Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)
Peter A. McCullough, Paul E. Alexander, Robin Armstrong, Cristian Arvinte, Alan F. Bain, Richard P. Bartlett, Robert L. Berkowitz, Andrew C. Berry, Thomas J. Borody, Joseph H. Brewer, Adam M. Brufsky, Teryn Clarke, Roland Derwand, Alieta Eck, John Eck, Richard A. Eisner, George C. Fareed, Angelina Farella, Silvia N. S. Fonseca, Charles E. Geyer, Jr., Russell S. Gonnering, Karladine E. Graves, Kenneth B. V. Gross, Sabine Hazan, Kristin S. Held, H. Thomas Hight, Stella Immanuel, Michael M. Jacobs, Joseph A. Ladapo, Lionel H. Lee, John Littell, Ivette Lozano, Harpal S. Mangat, Ben Marble, John E. McKinnon, Lee D. Merritt, Jane M. Orient, Ramin Oskoui, Donald C. Pompan, Brian C. Procter, Chad Prodromos, Juliana Cepelowicz Rajter, Jean-Jacques Rajter, C. Venkata S. Ram, Salete S. Rios, Harvey A. Risch, Michael J. A. Robb, Molly Rutherford, Martin Scholz, Marilyn M. Singleton, James A. Tumlin, Brian M. Tyson, Richard G. Urso, Kelly Victory, Elizabeth Lee Vliet, Craig M. Wax, Alexandre G. Wolkoff, Vicki Wooll, Vladimir Zelenko
Table 1. Listing of early home-based treatment kits provided for acute COVID-19 illness by various countries.
Country Drugs and supplements References
Algeria Chloroquine/Hydroxychloroquine (Belayneh, 2020)
Argentina Ivermectin (Mega, 2020)
Brazil Hydroxychloroquine, Ivermectin, Azithromycin (Vitamin D and zinc only for those who can afford) (Ministério da Saúde, 2020; Coronavirus a Tarde, 2020)
Bangladesh Ivermectin, Doxycycline (Trial Site News, 2020)
Cameroon Chloroquine/Hydroxychloroquine (Belayneh, 2020; Bösmüller et al., 2020)
China Chloroquine/Hydroxychloroquine plus other traditional medicine up to 23 different Chinese herbal medicines (Fan et al., 2020)
Colombia Ivermectin (Mega, 2020)
Egypt Chloroquine/Hydroxychloroquine (Mohhamad, 2020)
France Hydroxychloroquine, Azithromycin, and Lopinavir-Ritonavir (Gérard et al., 2020)
Ghana Chloroquine/Hydroxychloroquine (Isaac, 2020)
India Hydroxychlorquine, Ivermectin, alone or in combination with other drugs (Vora et al., 2020)
Korea Hydroxychloroquine (Hong et al., 2020)
Mexico Ivermectin, hydroxychloroquine (Pacheco, 2020)
Morocco Chloroquine/Hydroxychloroquine (McFadyen et al., 2020; Mussa, 2020; Brian, 2020)
Mozanbique Chloroquine/Hydroxychloroquine (McFadyen et al., 2020; Belayneh, 2020)
Nigeria Chloroquine/Hydroxychloroquine (McFadyen et al., 2020; Felix, 2020)
Peru Ivermectin, Azithromycin (Diario oficial del bicentenario, 2020; Trial Site News, 2020)
Senegal Chloroquine/Hydroxychloroquine (McFadyen et al., 2020; Huaxia, 2020)
South Africa Chloroquine/Hydroxychloroquine (McFadyen et al., 2020; Katharine, 2020)
Spain Patients who are already taking hydroxychloroquine within or outside of clinical trials for COVID-19 as well as patients undergoing chronic treatment with these drugs should continue taking them and, in any case, maintain their usual follow-ups with their doctors (Agencia Española de Medicamentos y Productos Sanitarios, 2020)
Taiwan Hydroxychloroquine (Sheng, 2020)
Uganda Chloroquine/Hydroxychloroquine, Azithromycin (McFadyen et al., 2020; The Independent, 2020)
USA No kits provided from public health agencies, Association of American Physicians and Surgeons Home COVID-19 Treatment Guide recommendends adjuvant neutraceuticals, and sequenced multidrug therapy by prescription (AAPS, 2020)